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N-Acetyl Epithalon Amidate PureRawz
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PureRawz

N-Acetyl Epithalon Amidate PureRawz

Rs.48,040.00 Rs.50,442.00 5% Off


N-Acetyl Epithalon Amidate (Ac-AEDG-NH2)  Overview

N-Acetyl Epithalon Amidate (Ac-AEDG-NH2) is a research-grade synthetic tetrapeptide. It is derived from the parent compound Epithalon (Epitalon), originally characterized from the bovine pineal gland.  It's an investigational compound and is not approved for clinical use.  It is supplied exclusively for controlled laboratory and in vitro research applications. The compound has a four-amino-acid sequence Alanine-Glutamic acid-Aspartic acid-Glycine (AEDG) of the parent peptide. In addition, it has two deliberate structural modifications that researchers believe significantly enhance its physicochemical profile for research settings. 


Product Code VDF-66
Availability In Stock
Type Spray
Category N-Acetyl Epithalon Amidate
Brand PureRawz
Shipping 01 day shipping. (Free pickup today)

PureRawz N-Acetyl Epithalon Amidate (Ac-AEDG-NH2)

PureRawz N-Acetyl Epithalon Amidate (Ac-AEDG-NH2) is a high-quality synthetic tetrapeptide developed for advanced laboratory research. Derived from the parent peptide Epithalon (Epitalon), this modified compound incorporates structural enhancements designed to improve molecular stability and resistance to enzymatic degradation.

Its peptide sequence consists of Alanine, Glutamic Acid, Aspartic Acid, and Glycine (AEDG), while N-terminal acetylation and C-terminal amidation provide greater physicochemical stability, making it highly suitable for controlled research environments.

Researchers commonly investigate this compound in studies involving cellular aging pathways, telomere biology, oxidative stress, peptide engineering, and circadian rhythm signaling.


Key Features

  • Premium-quality research peptide from PureRawz.
  • Modified Epithalon analog with enhanced stability.
  • N-terminal acetylation and C-terminal amidation.
  • High purity of ≥98% verified through HPLC analysis.
  • Suitable for molecular and biochemical research.
  • Commonly studied in telomere and longevity-related pathways.
  • Certificate of Analysis available for quality verification.
  • Manufactured to strict research-grade standards.

Structural Modifications for Enhanced Stability

N-Terminal Acetylation

The addition of an acetyl group at the N-terminus helps increase peptide stability by reducing susceptibility to aminopeptidase degradation. This modification contributes to improved consistency and performance during laboratory analysis.

C-Terminal Amidation

C-terminal amidation converts the terminal carboxyl group into an amide group, enhancing resistance to enzymatic breakdown and supporting peptide integrity during experimental studies.

Together, these modifications provide superior stability compared to the parent Epithalon peptide.


Proposed Mechanism of Action

Epigenetic Research

N-Acetyl Epithalon Amidate is being investigated for its interactions with chromatin-associated structures and gene transcription pathways. Preclinical models have explored its role in regulating molecular signaling and cellular processes.

Telomere and Telomerase Studies

Researchers have studied this peptide for its involvement in telomerase-associated pathways and telomere maintenance mechanisms. These investigations contribute to understanding cellular longevity and proliferative capacity under laboratory conditions.

Oxidative Stress Research

Experimental models have evaluated the compound's effects on oxidative stress markers and endogenous antioxidant signaling pathways, providing insight into cellular defense mechanisms.

Circadian Rhythm Investigations

The peptide has attracted scientific interest in studies involving pineal gland signaling, clock gene expression, and molecular mechanisms associated with circadian rhythm regulation.


Potential Research Applications

Cellular Aging and Longevity Research

Epithalon analogs are commonly investigated in studies involving:

  • Cellular senescence pathways.
  • Telomere biology.
  • Gene expression mechanisms.
  • Molecular longevity research.

Circadian Rhythm and Pineal Signaling

Researchers utilize this peptide in controlled studies examining:

  • Melatonin-associated pathways.
  • Pineal gland peptide interactions.
  • Circadian signaling mechanisms.

Oxidative Stress and DNA Stability

The compound is also used in investigations related to:

  • Oxidative stress biomarkers.
  • Genomic stability.
  • Cellular protection pathways.

Peptide Engineering

Due to its modified structure, N-Acetyl Epithalon Amidate is frequently studied for:

  • Proteolytic resistance.
  • Peptide stability.
  • Structure-function relationships.
  • Molecular delivery characteristics.

Biochemical and Receptor Studies

Researchers incorporate this peptide into:

  • Receptor-binding experiments.
  • Peptide characterization workflows.
  • Cellular pathway investigations.
  • Molecular pharmacology research.

Why Choose PureRawz N-Acetyl Epithalon Amidate?

PureRawz is recognized worldwide for producing premium-quality research compounds with exceptional purity and consistency. Every batch undergoes rigorous quality control and third-party verification to ensure researchers receive reliable materials for advanced scientific studies.

Benefits include:

  • ≥98% purity verified by HPLC.
  • Batch-specific Certificate of Analysis.
  • Enhanced peptide stability.
  • Strict quality standards.
  • Reliable manufacturing consistency.
  • Trusted by research professionals.

At nexacore.pk, customers throughout Pakistan can access premium peptides, SARMs, nootropics, and performance-enhancement research compounds from trusted international brands. We are committed to providing authentic products, competitive pricing, and dependable service to researchers seeking top-quality research materials.


Product Specifications

Specification Details
Compound Name N-Acetyl Epithalon Amidate
Alternative Name Ac-AEDG-NH2
Peptide Sequence Ala-Glu-Asp-Gly
Molecular Formula C14H22N4O9
Molecular Weight 390.35 g/mol
CAS Number 307297-39-8
Classification Synthetic Tetrapeptide
Structural Modifications N-Terminal Acetylation and C-Terminal Amidation
Purity ≥98%
Storage Conditions -20°C, Protected from Light and Moisture
Brand PureRawz

Handling and Storage

For optimal stability, N-Acetyl Epithalon Amidate should be stored at -20°C and protected from moisture, heat, and light exposure. Avoid repeated freeze-thaw cycles and handle using appropriate laboratory safety procedures, including gloves, protective clothing, and eye protection.

Disclaimer

PureRawz N-Acetyl Epithalon Amidate (Ac-AEDG-NH2) is intended strictly for laboratory and research purposes only. This product is not approved for human consumption, veterinary use, or therapeutic applications. The information provided is for educational purposes and should not be interpreted as medical advice or treatment recommendations.

 

FAQs

Will the product look exactly like the picture?
No — product appearance may vary. We import products and the actual item can differ slightly from the listing image.
Where do you ship?
We deliver only within Pakistan.
What payment methods are available?
Cash On Delivery (COD) and direct payment (bank transfer or other direct methods) as agreed at checkout.
Do you confirm orders before shipping?
Yes — we will call to confirm order details before processing and shipping.
Which courier services do you use?
TCS, M&P and Leopards (depending on destination and availability).
Are the products genuine?
Yes — products are original as supplied by our vendors and import partners.
How long does delivery take?
Typically 1–4 working days after order confirmation.
Can I change or cancel my order?
Contact us ASAP. We can often make changes during the confirmation call.

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